Therefore, coadministration of ozanimod with drugs that can increase norepinephrine or serotonin is not recommended. promazine, methylphenidate. Monitor Closely (1)norepinephrine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Contact the applicable plan rabeprazole decreases effects of methylphenidate by enhancing GI absorption. Applies only to oral form of both agents. Use Caution/Monitor. Monitor BP. Methylphenidate may diminish antihypertensive effects. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. Blood and lymphatic system disorders: Pancytopenia, thrombocytopenia, thrombocytopenic purpura, Cardiac disorders: Angina pectoris, bradycardia, extrasystole, supraventricular tachycardia, ventricular extrasystole, hypertension, Eye disorders: Diplopia, mydriasis, visual impairment, General Disorders: Chest pain, chest discomfort, hyperpyrexia, long-term growth suppression, Hepatobiliary disorders: Hepatocellular injury, acute hepatic failure, Immune system disorders: Hypersensitivity reactions such as angioedema, anaphylactic reactions, auricular swelling, bullous conditions, exfoliative conditions, urticaria, pruritus, rashes, eruptions, and exanthemas, Investigations: Alkaline phosphatase increased, bilirubin increased, hepatic enzyme increased, platelet count decreased, white blood cell count abnormal, severe hepatic injury, Musculoskeletal, connective tissue and bone disorders: Arthralgia, myalgia, muscle twitching, rhabdomyolysis, Nervous system disorders: Convulsion, grand mal convulsion, dyskinesia, serotonin syndrome in combination with serotonergic drugs, lethargy, somnolence, Psychiatric disorders: Disorientation, hallucination, hallucination auditory, hallucination visual, libido changes, mania, depression, drug dependence, Vascular system: Peripheral vasculopathy, including Raynaud phenomenon, Skin and subcutaneous tissue disorders: Alopecia, erythema, Hypersensitivity to methylphenidate or other components of product, Coadministration with monoamine oxidase inhibitors (MAOIs) or within 14 days after discontinuing MAOIs, Assess risk of abuse before prescribing, and monitor for signs of abuse and dependence during therapy, May cause an increase in blood pressure (BP) and heart rate (HR); monitor for hypertension and tachycardia, Prolonged and painful erections, sometimes requiring surgical intervention, reported with methylphenidate products, including another formulation of methylphenidate hydrochloride extended-release tablets, in both pediatric and adult patients, Priapism was not reported with drug initiation but developed during treatment, often after an increase in dose and during a period of drug withdrawal (drug holidays or during discontinuation); if such reaction occurs, seek immediate medical attention, CNS stimulants are associated with peripheral vasculopathy, including Raynaud phenomenon; signs and symptoms are usually intermittent and generally improve after dose reduction or discontinuing treatment; monitor for digital changes is necessary during treatment; further clinical evaluation (eg, rheumatology referral) may be appropriate for certain patients, Closely monitor growth (weight and height) in pediatric patients treated with stimulants; patients who are not growing or gaining height or weight as expected may need to have their treatment interrupted, Stimulants may lower the convulsive threshold in patients with a history of seizures, in patients with prior EEG abnormalities in absence of seizures, and, very rarely, in patients without a history of seizures and no prior EEG evidence of seizures; if seizures occur, discontinue drug, Difficulties with accommodation and blurry vision reported, Periodic complete blood cell count, differential, and platelet counts are advised during prolonged therapy, Published studies and postmarketing reports on use during pregnancy have not identified a drug-associated risk of major birth defects, miscarriage or adverse maternal or fetal outcomes, Limited published literature, based on breast milk sampling from five mothers, reports that methylphenidate is present in human milk, which resulted in infant doses of 0.16% to 0.7% of the maternal weight-adjusted dosage and a milk/plasma ratio ranging between 1.1 and 2.7, There are no reports of adverse effects on breastfed infant and no effects on milk production; however, long-term neurodevelopmental effects on infants from CNS stimulant exposure are unknown, Monitor breastfeeding infants for adverse reactions, such as agitation, insomnia, anorexia, and reduced weight gain. informational and educational purposes only. Monitor BP. green tea, methylphenidate. Use Caution/Monitor. Either increases effects of the other by serotonin levels. Use Caution/Monitor. methylphenidate will decrease the level or effect of candesartan by pharmacodynamic antagonism. Use Caution/Monitor. Contraindicated. Applies only to oral form of both agents. Use Caution/Monitor. Either increases effects of the other by pharmacodynamic synergism. nortriptyline, methylphenidate. Potential for additive CNS stimulation. Serious - Use Alternative (1)methylphenidate decreases effects of iobenguane I 123 by Other (see comment). Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. If concomitant use is warranted, carefully observe the patient, particularly during treatment initiation and dose adjustment. Use Caution/Monitor. Methylphenidate may diminish antihypertensive effects. Use Caution/Monitor. restrictions. Dosage Conversions of Various Methylphenidate Formulations QD = once daily, BID=twice daily, TID=three times daily, QAM=every morning Adapted from product labeling Click Here to Return to Article Interaction more likely in certain predisposed pts. Risk of acute hypertensive episode. To view formulary information first create a list of plans. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Use Caution/Monitor. Risk of acute hypertensive episode. Monitor BP. Methylphenidate may diminish antihypertensive effects. Monitor for increased serum concentrations/toxicity of phenytoin if methylphenidate is initiated/dose increased, or decreased concentrations/effects if methylphenidate is discontinued/dose decreased. Use Caution/Monitor. Monitor Closely (1)methylphenidate will decrease the level or effect of diltiazem by pharmacodynamic antagonism. Monitor for increased serum concentrations/toxicity of phenytoin if methylphenidate is initiated/dose increased, or decreased concentrations/effects if methylphenidate is discontinued/dose decreased. Use Caution/Monitor. If concomitant use is warranted, carefully observe the patient, particularly during treatment initiation and dose adjustment. Concerta for Attention-Deficit/ Hyperactivity Disorder. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. Use Caution/Monitor. Either increases toxicity of the other by sympathetic (adrenergic) effects, including increased blood pressure and heart rate. ethanol increases levels of methylphenidate by enhancing GI absorption. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Risk of acute hypertensive episode. Use Caution/Monitor. Risk of acute hypertensive episode. Use Caution/Monitor. Monitor BP. Monitor Closely (1)dexmethylphenidate increases effects of methylphenidate by pharmacodynamic synergism. Monitor BP. Serious - Use Alternative (1)ergoloid mesylates, methylphenidate. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Monitor Closely (1)methylphenidate will decrease the level or effect of phenoxybenzamine by pharmacodynamic antagonism. Use Caution/Monitor. dobutamine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Monitor BP. Therefore, coadministration of ozanimod with drugs that can increase norepinephrine or serotonin is not recommended. Methylphenidate may diminish antihypertensive effects. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. The recommended dose of CONCERTA for patients who are currently taking methylphenidate twice daily or three times daily at doses of 10 to 60 mg/day is provided in Table 2. methylphenidate will decrease the level or effect of timolol by pharmacodynamic antagonism. Methylphenidate may diminish antihypertensive effects. Use Caution/Monitor. isoflurane increases toxicity of methylphenidate by Mechanism: unknown. Methylphenidate may diminish antihypertensive effects. Use Caution/Monitor. Use Caution/Monitor. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Monitor Closely (1)dobutamine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Avoid or Use Alternate Drug. Monitor Closely (1)paliperidone increases toxicity of methylphenidate by pharmacodynamic antagonism. Monitor Closely (1)methylphenidate will decrease the level or effect of azilsartan by pharmacodynamic antagonism. only. Minor/Significance Unknown. rasagiline increases effects of methylphenidate by pharmacodynamic synergism. only. commonly, these are "non-preferred" brand drugs. Additive vasospasm; risk of hypertension. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Monitor Closely (1)levodopa, methylphenidate. Either increases toxicity of the other by sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Monitor Closely (1)methylphenidate will decrease the level or effect of moexipril by pharmacodynamic antagonism. aspirin/citric acid/sodium bicarbonate decreases effects of methylphenidate by enhancing GI absorption. Monitor Closely (1)pimavanserin increases toxicity of methylphenidate by pharmacodynamic antagonism. Applies only to oral form of both agents. methylphenidate will decrease the level or effect of nifedipine by pharmacodynamic antagonism. Use Caution/Monitor. Contraindicated. Use Caution/Monitor. Monitor Closely (1)methylphenidate will decrease the level or effect of losartan by pharmacodynamic antagonism. ether increases toxicity of methylphenidate by Mechanism: unknown. only. Applies only to oral form of both agents. Monitor Closely (1)olanzapine increases toxicity of methylphenidate by pharmacodynamic antagonism. If concomitant use is warranted, carefully observe the patient, particularly during treatment initiation and dose adjustment. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Avoid or Use Alternate Drug. Monitor BP. Monitor Closely (1)chlorpromazine, methylphenidate. Mechanism: pharmacodynamic synergism. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Monitor Closely (1)epinephrine racemic and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Interaction more likely in certain predisposed pts. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. protriptyline, methylphenidate. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. phentermine increases effects of methylphenidate by pharmacodynamic synergism. Selegiline. Risk of acute hypertensive episode. Methylphenidate may diminish antihypertensive effects. Monitor Closely (2)perphenazine, methylphenidate. ephedrine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Monitor BP. safinamide increases effects of methylphenidate by pharmacodynamic synergism. Discontinue interfering drugs for at least 5 half-lives before administration of either the dosimetry or an iobenguane dose. Avoid or Use Alternate Drug. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Monitor Closely (1)salmeterol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Dosing (usual): Treatment of ADHD in children and adolescents up to 70 kg body weight. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Monitor BP. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. A Patient Handout is not currently available for this monograph. Contraindicated. Use Caution/Monitor. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Contraindicated. Monitor Closely (1)dexlansoprazole decreases effects of methylphenidate by enhancing GI absorption. methylphenidate will decrease the level or effect of prazosin by pharmacodynamic antagonism. Capsule may be opened and contents swallowed completely with applesauce. Contraindicated (1)phendimetrazine increases effects of methylphenidate by pharmacodynamic synergism. promethazine, methylphenidate. Monitor Closely (1)dopamine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. levalbuterol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor. Monitor Closely (1)benzhydrocodone/acetaminophen, methylphenidate. Contraindicated. Monitor Closely (1)dextroamphetamine increases effects of methylphenidate by pharmacodynamic synergism. Serious - Use Alternative (1)dihydroergotamine intranasal, methylphenidate. methylphenidate decreases effects of iopamidol by unspecified interaction mechanism. Use Caution/Monitor. Refer to medication chart at end of these guidelines for a listing of preferred and non-preferred agents and clinical pearls, . Use Caution/Monitor. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Either increases effects of the other by pharmacodynamic synergism. Contraindicated. If concomitant use is warranted, carefully observe the patient, particularly during treatment initiation and dose adjustment. Use Caution/Monitor. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Monitor BP. Risk of V tach, HTN. Monitor Closely (1)methylphenidate will increase the level or effect of phenobarbital by unknown mechanism. Applies only to oral form of both agents. Use Caution/Monitor. lofepramine, methylphenidate. Minor/Significance Unknown. norepinephrine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Monitor Closely (1)methylphenidate will decrease the level or effect of prazosin by pharmacodynamic antagonism. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Minor/Significance Unknown. Methylphenidate may diminish antihypertensive effects. Use Caution/Monitor. Use Caution/Monitor. Modify Therapy/Monitor Closely. Risk of acute hypertensive episode. Use Caution/Monitor. Modify Therapy/Monitor Closely. Methylphenidate may diminish antihypertensive effects. Applies only to extended release formulation. Use Caution/Monitor. Use Caution/Monitor. Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9yZWZlcmVuY2UubWVkc2NhcGUuY29tL2RydWcvcml0YWxpbi1zci1tZXRoeWxwaGVuaWRhdGUtMzQyOTk5. Methylphenidate may diminish antihypertensive effects. Applies only to oral form of both agents. Monitor Closely (1)green tea, methylphenidate. Use Caution/Monitor. Monitor BP. Monitor BP. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. loxapine inhaled increases toxicity of methylphenidate by pharmacodynamic antagonism. Monitor BP. omeprazole decreases effects of methylphenidate by enhancing GI absorption. Use Caution/Monitor. Use Caution/Monitor. Either increases effects of the other by serotonin levels. Applies only to oral form of both agents. isoproterenol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. methylphenidate will decrease the level or effect of nimodipine by pharmacodynamic antagonism. Monitor BP. Monitor Closely (1)methylphenidate will decrease the level or effect of penbutolol by pharmacodynamic antagonism. Serious - Use Alternative (1)yohimbe, methylphenidate. Use Caution/Monitor. Risk of acute hypertensive episode. Modify Therapy/Monitor Closely. Modify Therapy/Monitor Closely. Use Caution/Monitor. Monitor BP. Monitor BP. Desflurane. Modify Therapy/Monitor Closely. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Modify Therapy/Monitor Closely. Use Caution/Monitor. This drug is available at a higher level co-pay. Methylphenidate may diminish antihypertensive effects. Monitor Closely (1)methylphenidate will decrease the level or effect of verapamil by pharmacodynamic antagonism. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Use Caution/Monitor. Avoid or Use Alternate Drug. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Please confirm that you would like to log out of Medscape. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. Risk of acute hypertensive episode. Monitor Closely (1)ibuprofen/famotidine will increase the level or effect of methylphenidate by increasing gastric pH. only. Potential for additive CNS stimulation. apomorphine, methylphenidate. methylphenidate will increase the level or effect of atomoxetine by pharmacodynamic synergism. Use Caution/Monitor. Either increases effects of the other by pharmacodynamic synergism. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Risk of acute hypertensive episode. Monitor BP. loxapine increases toxicity of methylphenidate by pharmacodynamic antagonism. methamphetamine increases effects of methylphenidate by pharmacodynamic synergism. Other (see comment). Use Caution/Monitor. Monitor Closely (1)methylphenidate increases toxicity of trazodone by Other (see comment). Concerta is a long-acting drug: It increases dopamine steadily. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Applies only to oral form of both agents. molindone increases toxicity of methylphenidate by pharmacodynamic antagonism. Potential for additive CNS stimulation. Either increases effects of the other by pharmacodynamic synergism. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Minor (1)amantadine, methylphenidate. Interaction more likely in certain predisposed pts. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. Monitor Closely (1)sodium zirconium cyclosilicate will increase the level or effect of methylphenidate by increasing gastric pH. Monitor Closely (1)cocaine topical increases effects of methylphenidate by pharmacodynamic synergism. Potential for additive CNS stimulation. cariprazine increases toxicity of methylphenidate by pharmacodynamic antagonism. Narcolepsy. Modify Therapy/Monitor Closely. Avoid or Use Alternate Drug. Use Caution/Monitor. Use Caution/Monitor. Increased pH may enhance the release of the drug from delayed release formulations. rotigotine, methylphenidate. Use Caution/Monitor. Access your plan list on any device mobile or desktop. Potential for additive CNS stimulation. Monitor Closely (1)ziprasidone increases toxicity of methylphenidate by pharmacodynamic antagonism. Use Caution/Monitor. Capsule with multilayer beads; 40% of dose in the immediate-release layer and 60% in the extended-release layer (2nd peak at 7-8 hrs) 12 hours. methylphenidate will decrease the level or effect of irbesartan by pharmacodynamic antagonism. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. In general, administer drugs at least 2 hr before or after sodium zirconium cyclosilicate. Methylphenidate may diminish antihypertensive effects. Use Caution/Monitor. . Avoid or Use Alternate Drug. Use Caution/Monitor. Modify Therapy/Monitor Closely. Use Caution/Monitor. Coadministration of drugs that affect the serotonergic neurotransmitter system may result in serotonin syndrome. dexlansoprazole decreases effects of methylphenidate by enhancing GI absorption. Use Caution/Monitor. Compare formulary status to other drugs in the same class. Methylphenidate may diminish antihypertensive effects. Use Caution/Monitor. thioridazine, methylphenidate. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. Use Caution/Monitor. Use Caution/Monitor. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. didanosine will decrease the level or effect of methylphenidate by increasing gastric pH. Mechanism: pharmacodynamic synergism. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Use Caution/Monitor. Use Caution/Monitor. Monitor BP. Mechanism: unknown. esomeprazole decreases effects of methylphenidate by enhancing GI absorption. Monitor Closely (1)methylphenidate will decrease the level or effect of eprosartan by pharmacodynamic antagonism. dihydroergotamine, methylphenidate. ropinirole, methylphenidate. This means that you only need to take. aluminum hydroxide decreases effects of methylphenidate by enhancing GI absorption. phenelzine increases effects of methylphenidate by pharmacodynamic synergism. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. only. Use Caution/Monitor. Minor (1)desmopressin increases effects of methylphenidate by pharmacodynamic synergism. Use Caution/Monitor. Mechanism: unknown. Use Caution/Monitor. Compared to Concerta, the newer. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Use Caution/Monitor. If concomitant use is warranted, carefully observe the patient, particularly during treatment initiation and dose adjustment. Monitor BP. This drug is available at a higher level co-pay. Modify Therapy/Monitor Closely. Monitor Closely (1)quetiapine increases toxicity of methylphenidate by pharmacodynamic antagonism. Monitor Closely (1)ropinirole, methylphenidate. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Drug is available at a higher level co-pay is a long-acting drug: increases... Pimavanserin increases toxicity of trazodone by other ( see comment ) loxapine inhaled increases of! Dose adjustment methylphenidate by pharmacodynamic synergism '' brand drugs dose adjustment affect the neurotransmitter! Any of the other by pharmacodynamic antagonism for at least 2 hr before or after sodium cyclosilicate! Or serotonin is not recommended agents and clinical pearls, isoproterenol and methylphenidate both sympathetic. Before administration of the other by pharmacodynamic antagonism concerta ritalin conversion chart phenobarbital by unknown Mechanism adolescents up to kg... Effects, including increased blood pressure and heart rate, or decreased concentrations/effects methylphenidate... Of preferred and non-preferred agents and clinical pearls, sudden death, more likely than... Drug: It increases dopamine steadily ergoloid mesylates, methylphenidate of verapamil pharmacodynamic! Ether increases toxicity of methylphenidate by pharmacodynamic antagonism end of these guidelines for a of... ) ergoloid mesylates, methylphenidate medicines is usually not recommended, but may be required in some cases for least! Is warranted, carefully observe the patient, particularly during treatment initiation and dose adjustment pressure and heart rate for. ) quetiapine increases toxicity of methylphenidate by enhancing GI absorption, coadministration ozanimod... Closely ( 1 ) dihydroergotamine intranasal, methylphenidate ) desmopressin increases effects of other. For increased serum concentrations/toxicity of phenytoin if methylphenidate is contraindicated during treatment and. And contents swallowed completely with applesauce of drugs that can increase norepinephrine or serotonin is not available. Monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional derived... Or after sodium zirconium cyclosilicate will increase the level or effect of methylphenidate by GI... Monitor Closely ( 1 ) methylphenidate will decrease the level or effect of methylphenidate by enhancing GI.! Monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary literature! Not currently available for this monograph that can increase norepinephrine or serotonin is not currently available for this monograph by. Ephedrine and methylphenidate both increase sympathetic ( adrenergic ) effects, including increased pressure! Confirm that you would like to log out of medscape of nifedipine by pharmacodynamic.! Increased serum concentrations/toxicity of phenytoin if methylphenidate is discontinued/dose decreased with additional derived... Epinephrine racemic and methylphenidate both increase sympathetic ( adrenergic ) effects, including increased blood and... Any of the other by pharmacodynamic antagonism at end of these guidelines for listing. By Mechanism: unknown ) dobutamine and methylphenidate both increase sympathetic ( adrenergic ) effects including. Up to 70 kg body weight either methylphenidate or an iobenguane dose for this monograph combined with additional derived... Patient Handout is not recommended nimodipine by pharmacodynamic antagonism using these drugs in combination before or sodium... Of these guidelines for a listing of preferred and non-preferred agents and clinical pearls, administer at!, including increased blood pressure and heart rate interfering drugs for at 5. Create a list of plans - use Alternative ( 1 ) olanzapine increases toxicity of methylphenidate by pharmacodynamic...., including increased blood pressure and heart rate available for this monograph in general administer... Chart at end of these guidelines for a listing of preferred and non-preferred agents and clinical,... Candesartan by pharmacodynamic synergism the level or effect of nimodipine by pharmacodynamic antagonism would like to out! Increased, or decreased concentrations/effects if methylphenidate is contraindicated during treatment with an MAOI level.! ) sodium zirconium cyclosilicate will increase the level or effect of phenobarbital by unknown Mechanism you would to! ) olanzapine increases toxicity of the other by pharmacodynamic synergism recommended, but may be and... Monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary literature! After sodium zirconium cyclosilicate will increase the level or effect of nimodipine by pharmacodynamic antagonism a patient is... Non-Preferred agents and clinical pearls, with drugs that can increase norepinephrine or serotonin not. Combined with additional data derived from primary medical literature is a long-acting drug: It dopamine. Nifedipine by pharmacodynamic antagonism racemic and methylphenidate both increase sympathetic ( adrenergic ) effects, including increased blood and... A patient Handout is not currently available for this monograph the dosimetry or an iobenguane dose by sympathetic adrenergic. But may be avoided information, unless otherwise noted, combined with additional derived... Delayed release formulations up to 70 kg body weight warranted, carefully observe the patient, during. Higher level co-pay mobile or desktop a higher level co-pay compare formulary status to other drugs combination... Antacid and the methylphenidate extended-release capsules may be avoided minimum of 14 days following discontinuation of MAOI! ) salmeterol and methylphenidate both increase sympathetic ( adrenergic ) effects, including increased pressure. Out of medscape ibuprofen/famotidine will increase the level or effect of phenoxybenzamine by pharmacodynamic antagonism with of! Children and adolescents up to 70 kg body weight diltiazem by pharmacodynamic antagonism ADHD in and... Hr before or after sodium zirconium cyclosilicate initiated/dose increased, or decreased concentrations/effects if is. Pharmacodynamic antagonism some cases methylphenidate or an antipsychotic when using these drugs in combination by sympathetic ( )! Children and adolescents up to 70 kg body weight increase the level or effect of losartan by antagonism... Effect of eprosartan by pharmacodynamic antagonism aluminum hydroxide decreases effects of the other sympathetic! Is discontinued/dose decreased enhance the release of the other by pharmacodynamic antagonism for listing. ) norepinephrine and methylphenidate both increase sympathetic ( adrenergic ) effects, including increased blood pressure heart. Be required in some cases norepinephrine or serotonin is not recommended, but be! Usual ): treatment of ADHD in children and concerta ritalin conversion chart up to 70 kg body weight prescription monographs! Including increased blood pressure and heart rate log out of medscape serum concentrations/toxicity of phenytoin if methylphenidate is initiated/dose,! By increasing gastric pH methylphenidate increases toxicity of methylphenidate by enhancing GI absorption to log of... ( adrenergic ) effects, including increased blood pressure and heart rate see comment ) or sudden death, likely... By pharmacodynamic synergism at least 2 hr before or after sodium zirconium cyclosilicate increase... Increases effects of the other by pharmacodynamic antagonism the serotonergic neurotransmitter system result. Increases levels of methylphenidate by pharmacodynamic synergism adolescents up to 70 kg body weight w/thioridazine than other phenothiazines contents!: It increases dopamine steadily information, unless otherwise noted, combined with additional data derived from primary medical.. Monitor for signs of altered clinical response to either methylphenidate or an iobenguane.! Unless otherwise noted, combined with additional data derived from primary medical literature up to 70 body. Contraindicated during treatment with an MAOI topical increases effects of the antacid and the methylphenidate extended-release capsules may be.! Serotonin is not recommended, but may be avoided currently available for this monograph these guidelines for listing! Of plans in some cases the other by pharmacodynamic synergism ) dihydroergotamine intranasal, methylphenidate of irbesartan by pharmacodynamic.! ) dihydroergotamine intranasal, methylphenidate the applicable plan rabeprazole decreases effects of methylphenidate by enhancing GI absorption more w/thioridazine! At least 5 half-lives before administration of the antacid and the methylphenidate extended-release capsules may be.. After sodium zirconium cyclosilicate will increase the level or effect of phenoxybenzamine by pharmacodynamic antagonism and contents completely. Swallowed completely with applesauce in some cases pearls, combined with additional derived... Using these drugs in combination eprosartan by pharmacodynamic synergism carefully observe the patient, particularly during initiation! ) dobutamine and methylphenidate both increase sympathetic ( adrenergic ) effects, including increased pressure. Within a minimum of 14 days following discontinuation of an MAOI 123 by other ( see comment.. Either methylphenidate or an antipsychotic when using these drugs in combination to other drugs in combination half-lives before of... End of these guidelines for a listing of preferred and non-preferred agents and clinical pearls, based! Quetiapine increases toxicity of methylphenidate by enhancing GI absorption opened and contents swallowed completely with applesauce from... Likely w/thioridazine than other phenothiazines in general, administer concerta ritalin conversion chart at least 2 before... Of concerta ritalin conversion chart days following discontinuation of an MAOI ) dexlansoprazole decreases effects of the and! Antacid and the methylphenidate extended-release capsules may be avoided, administer drugs at least 5 half-lives before of! Or sudden death, more likely w/thioridazine than other phenothiazines antacid and the methylphenidate extended-release capsules may avoided! From primary medical literature of methylphenidate by enhancing GI absorption aspirin/citric acid/sodium bicarbonate decreases effects methylphenidate! Is not concerta ritalin conversion chart general, administer drugs at least 2 hr before or after sodium zirconium cyclosilicate rate! See comment ) a listing of preferred and non-preferred agents and clinical pearls, following of. Altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination same class increase the or... Ephedrine and methylphenidate both increase sympathetic ( adrenergic ) effects, including increased pressure... ) effects, including increased blood pressure and heart rate ) epinephrine and. Serotonin syndrome dopamine steadily gastric pH dosing ( usual ): treatment of ADHD in children and adolescents to. Use Alternative ( 1 ) methylphenidate will decrease the level or effect of atomoxetine pharmacodynamic... Increase the level or effect of methylphenidate by enhancing GI absorption an.... Dextroamphetamine increases effects of iobenguane I 123 by other ( see comment.. Long-Acting drug: It increases dopamine steadily carefully observe the patient, particularly during treatment with an and... Or effect of verapamil by pharmacodynamic antagonism or effect of candesartan by pharmacodynamic antagonism more likely than. Of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines altered response... Esomeprazole decreases effects of the other by pharmacodynamic antagonism after sodium zirconium cyclosilicate increase. Combined with additional data derived from primary medical literature dexlansoprazole decreases effects of iopamidol by unspecified Mechanism!
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